We have public institutions. Those exist.

Also, do you believe private institutions produce more science?

Certainly not investors, who's contribution takes place before the scientists', and without which the scientists' contribution couldn't exist.

I haven't heard that phrase before, "clinical corruption".

What's inbetween labor and consumers?

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I don't think you understand what the word "middleman" means.

> you already made up your mind apparently so i dont know why your here.

I find the argument made in the OP to be logical and persuasive.

> if you cant think of any possible reasons oxy was passed other then money then god help you (its not like oxy has any medical applications. ffs using your logic all painkillers are designed to make money. fuck me you probably think pharma likes cancer and wouldnt cure it if they could).

Oxycontin is more addictive with similar efficacy compared to other opioids. Why do you think it was pushed, if not for the billions of usd profit?

> It is a problem, but it is not like modern science is anywhere close to fraud

Within certain fields ie psychology, the meta studies mentioned in OP are showing 50% non reproducibility. That is a major problem.

Think about it - was oxycontin nonaddictive? Do SSRIs work? Vioxx? Phen-Phen? Adderall?

There is a crisis ongoing.

> You share the results so that the next trial done on the same patient population can be designed to yield an even better outcome and as part of the drug/device approval process.

So what went wrong with this process re: oxycontin? Why was that drug approval process so flawed?

Then you have no idea what you're talking. The replication crisis refers to a specific attempt to recreate major cornerstone studies in the field of psychology.

> Additionally, you’re fixated on just this oxy question for some reason.

Leading cause of death for 18-45 adults in usa. No big deal?

Being a middleman is not a contribution, it's a hindrance.

> eating is more important that holding to your ideals.

That is an extremely morally dubious claim.

Opioid overdoses are the #1 cause of death for adults 18-45 in usa... the Sacklers didn't make that happen without many accomplices with impressive science titles.

> When six out of seven of you experiments end in failure and the median cost for each failure is $20 million you'd think the process is very rigorous.

That's far from sufficient to consider the approval process rigorous, it's not even necessary. Particle Physics is very rigorous but still they don't fail more than six of seven experiments.

The solution to this paradox is that the reject rate doesn't tell you that much about the quality of the selection process. If at all it may reveal something about our collective ability to formulate correct hypotheses (based on understanding of the subject) for this experimental process.

>Religion is something people use to justify their suffering

Exactly. Which is just another way of saying they are searching for meaning. It feels less bad if there is an explanation and purpose for why all of this horrible shit is happening to you, especially if it also comes with a promise that soon the suffering will be over in exchange for an immense payoff in the afterlife.

>I think 99% of them want to be not starving and not be in a war first, lol.

Do they, though? I think there is some truth to the idea of religion being the opiate of the masses. The Catholic church is sitting on billions of dollars. Why don't the people in all the poor Catholic countries simply rise up and overthrow the Pope? And if you look throughout history, there have probably been way more people who have killed other innocent and suffering people or died themselves to protect their religion and religious leaders than tried to overthrow them.

Ring ring....

That whole comment just screams that you have absolutely no idea what you're talking about

Obviously not. You don't have to be a scientist to contribute to science though

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I think 99% of them want to be not starving and not be in a war first, lol.

Religion is something people use to justify their suffering, without suffering they wont care as much about god's plan and mysterious ways.

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You don’t think someone starving in a war torn country ever thinks about why they are suffering so bad and what is the point of all their pain? There’s a reason why poor people tend to be more religious.

I think that the meaninglessness of the world manifests itself in different ways to people of different income. And that some unfortunate people have physical problems/concerns in addition to metaphysical ones so that you cannot equate the two. But I do think that everyone suffers from the desire for meaning in a meaningless world. That’s a function of merely existing.

Dangerous drugs getting by is not the only issue, and as you point out, rarely happens. What does happen often is mediocre or simply ineffective treatments that are lauded due to financial incentive. This can happen even in highly controlled trials by over exaggerating moderate to mild findings to a public that either doesn’t have access to or doesn’t understand the literature. Also, all methods of data analysis have their flaws, and there are plenty of ways to both incidentally and purposefully end up with significant findings where there are none in reality.

And I’m glad you mention how the replication crisis is worse in psychology. I’m currently in graduate training to be a research psychologist, and the first month of our clinical research methods class has had a continual discussion of scientific integrity, how to identify flawed or overblown findings, and the danger (and reality) of financial incentive’s effects on research.

>You can conduct science publicly just as well as you can privately, nothing necessitates private organizations to being essential to creation of new science.

decades of brainwashing have convinced most people gov shouldnt run hospitals, prisons or schools ffs. these idiots think gov doing things is communism and automatically worse then private leechs doing the same thing +cost.

you mean gov does, these clowns pick up what we paid for then tweak and it pretend its their own 'innovation'.

nothing innovative about the millionth smartphone.